In Wistar rats kindled via repeated intraperitoneal corazol administration (25.0 mg/kg, i. p.) the reduction of the threshold of aggressive reactions precipitation was seen in test of pairs of animals fighting on electrode floor. L-arginin (150 mg/kg, i. p.) combined with ketogenic diet (KD) (2 weeks) caused the heightening of the threshold of aggressive reactions of rats while separatively applied they had no effects. Threshold raised by 72.7% in comparison with the initial level detected at stage of kindled seizures development. L-NAME (50.0 mg/kg, i. p.) induced significant reduction of the threshold of aggressive reactions both in intact and kindled rats, and abolished effects of RD.
