The aim of the work was to evaluate the influence of NO precursors on experimental animals at the prenatal stage. It is shown that exposure of female rats offspring for subtoxic doses of nitrates during pregnancy could cause adverse change such as reduced body weight in offspring by 10.0–12.0%, and reduced number of red blood cells in whole blood by 11.3% hemoglobin concentration — 14.5%. In addition, the percentage of pregnancies and the number of viable fetuses in female rats exposed to nitrate preconception stage and during pregnancy were also significantly lower than in intact animals.
