It was carried out the clinical observation, the assessment of medical documentation and the pedigree analysis of 140 patients with inflammatory bowel disease (IBD). The frequency of patients with colorectal cancer among the relatives of probands with inflammatory bowel disease was significantly higher than in patients of control group. Colorectal cancer was diagnosed in 9 (6.4%) persons. The males with disease history of more than 10 years with pronounced extraintestinal manifestations, pseudopolyps and positive familial anamnesis to colorectal cancer formed the group of high risk of IBD-associated cancer.
