It was examined the status of lipid transport system and its functional activity in patients with atherosclerosis under conditions of standard glucose load. It was revealed decrease of lipid transport system tolerance to carbohydrate load which manifested itself in violation of both direct and adverse cholesterol transport and lipoproteins exchange as a whole at the background of inadiquate lipoproteinlipase due to dicrease of efficiency of lipolysis in atherosclerosis patients. The patients with ischemic heart disease without clinical picture of atherosclerosis have dysbalance of lipoproteins with dicrease of content of cholesterol in high density lipoproteids and increase of cholesterol level in low density lipoprotein with low activity of lipoproteinlipase in response to glucose load can be considered as early signs of atherosclerotic process formation in this kind of patients.
