CLINICAL EFFECTS IN MANIFESTATIONS OF RADIATION REACTIONS OF THE ORAL MUCOUS MEMBRANE IN PATIENTS AFTER RADIATION THERAPY OF MALIGNANT NEOPLASMS IN THE AREA OF THE HEAD AND NECK AND THEIR REMOVAL

The application of the gel “Apident” in the complex therapy of radiation reactions of oral mucous membrane (OMM) in patients with neoplasms in the area of the head and neck after radiation treatment influenced favorably the objective and subjective symptoms of radiation reactions. There was observed fast fall in frequency of edema, OMM erosion, there were less often marked gingival hemorrhage, phenomena of focal and confluent epitheliitis, ulcerous-necrotic processes. There was noted reduction in the level of xerostomia manifestation, which promoted improvement of the oral hygienic condition, prevention of the secondary microbic colonization of the damaged mucous surfaces. The application of the gel “Apident” reduced terms of restoration of OMM structural-functional integrity, which improved life quality of patients and promoted their rehabilitation.