Streptozotocin (STC) (50.0 mg/kg, i. p.) diabetes was induced in Wistar rats glucose level higher than 300 mmol/l. In two weeks from the moment of STC administration treatment with delta-sleep inducing peptide (DSIP) (50.0 mcg/kg, i. p., daily) as well as treatment with electrical stimulation (ES) (100–300 Hz, twice per day) of paleocerebellar cortex started and lasted during two next weeks. Combined usage of DSIP and paleocerebellar ES caused potentiated elevation of thiol groups and reduced ascorbic acid in retina of rats with STC-induced experimental diabetes.
