The analysis of ophthalmoscope color images in macular zone in accordance to CIELAB scale have been undertaken in patients who suffered from type 2 diabetes during (4.5±0.3) years and who did not demonstrated the presence of microaneurisms as the most early mark of diabetic retinopathy. Obtained data on colors have been normalized pertained to the color characteristics of arterial retinal vessels. It was established that in patients with diabetes the increasing of the lightness was registered by 2.71 times when compared to control group (p<0.05). Besides, the integral color index difference ΔE exceeded that one which was registered in practically healthy patients 2.87 times (p<0.05). The microaneurisms appearance was controlled during the one year period from the moment of inclusion patients into observation. The correlation between ΔE initial values and dynamics of microaneurisms appearance was at value of coefficient r=-0.92. This result is in favor for the possibility of early diagnostics of diabetic retinopathy using proposed technology.
