The essentiality of the relations between terminal fragment of glycolysis, final step of the citric acid cycle and initial fragment of the gluconeogenesis in the myocardium and sceletal muscles of the experimental animals was investigated. Sceletal muscles have high level of the glycolytic processes. In comparison with sceletal muscles activity of CAC enzymes (NAD-MDH) is higher in the miocardial mitochondria. It is proved with the higher content of the malate and oxaloacetate as a metabolites of CAC and also activity of NADP-MDH. The ratio “lactate/pyruvate” and “malate/oxaloacetate” (they describe redox potential of nicotine amide coenzymes and can be used as a value of the oxigenation of tissues) evidences about the higher level of oxidation of the systeme NAD/NADH in the miocardium. It produced conditions for the intensive glycolysis and initial step of the gluconeogenesis in the sceletal muscles and high level of the CAC activity in the myocard of the experimental animals.
