The influence of cryopreserved placenta in experimental aseptic peritoneal inflammation in rats was investigated. Experiments were carried out on 50 sexually mature male rats. Experimental aseptic peritoneal inflammation was designed by injection of carragenin into abdominal cavity. Parts of animals with experimental aseptic inflammation were injected cryopreserved placenta single subcutaneously. The dynamics of change of morphometric parameters of the thickness of the mucous membrane of the different parts of the small intestine (the duodenum, jejunum, and ileum) was evaluated in experimental animals. It was established that single administration of cryopreserved placenta in experimental acute aseptic peritoneum inflammation helps to restore small intestine mucous membrane thickness up to intact rat’s parameters on the 14-th day of experiment. A maximum value of small intestine mucosa reactive thickening (15.3%) was observed on the 5-th day of the experiment (р<0.05). Cryopreserved placenta single subcutaneous injection equally effectively influenced on mucous membrane thickness of different parts of small intestine in experimental acute aseptic peritoneal inflammation.
