STUDYING THE PHASE OF THE HEPATOCYTES NUCLEI CELL CYCLE IN RATS OF DIFFERENT AGE GROUPS WITH CHRONIC ALCOHOLIC LIVER DAMAGE AND QUERCETIN AND L-ARGININE L-GLUTAMATE PHARMACOLOGICAL THERAPY

Alcoholic liver damage is common in Ukraine and has a high mortality rate. The paper presents the data to determine the age characteristics of the hepatocytes cell cycle in rats under chronic alcoholic liver damage. It was found that immature and old rats are the most sensitive to the toxic effects of ethanol in chronic alcohol intoxication hepatocytes. It is proved that young females mature rats have the highest defense mechanisms and reparative regeneration of the liver, while in old rats there is noted a significant decrease in mitotic activity.