We studied the state of glycolytic oxidoreduction in the myocardium and skeletal muscle in experimental animals of different age. It was measured the activity of glyceraldehyde-3-phosphate dehydrogenase, lactate dehydrogenase and its isoenzymes, and it was defined content of pyruvate and lactate. Through a comparative description of carbohydrate metabolism in skeletal muscles and myocardium of experimental animals of different age we established that in the competition for the glycolytic NADH, which is formed in the glyceraldehyde 3-phosphate dehydrogenase reaction, in skeletal muscle of adult rats and especially in skeletal muscle of young rats, dominates lactate dehydrogenase catalyzed reduction of pyruvate to lactate, which creates conditions for high glycolysis intensity.
