Contemopapry data on pathogenic mechanisms of diabetic retinopathy development are delivered and analyzed. Results on treatment with those compounds which demonstrate antioxidative activity are presented. Also critical data on effects of organic germanium compounds upon biological homeostasis are discussed. Author’s own results are in favor for the pronounced therapeutic effectiveness of the derivative of nicotinic acid-niacyn-oxyethiliden-diphosphonate-germinate [(NicH)2 [Ge(OH)2 (Oedph)] · H2O (MIGU-4) with regard to streptozotocin diabetes — induced electroretinogram deteriorations. Hence, gained data are perspective for MIGU-4 usage in the complex treatment of diabetic retinopathy.
