The article presents the results of clinical trials of 102 patients with Lyme borreliosis at different stages of the disease. There is established a great number of patients with various lesions of the nervous system. At the example of a definite clinical case of neuroborreliosis there is conducted analysis of the problems of diagnosis and treatment the nervous system lesions with Lyme borreliosis. It is demonstrated an expediency of specific methods using such as blot-analysis and study of cerebrospinal fluid on intrathecal synthesis of antibodies to borrelies in order to confirm etiologic factor of the nervous system defeat at Lyme borreliosis.
