The basis for this research was the data about 279 patients with regional forms of breast cancer and unfavorable predictive factors with stages T4N0-2M0, who were treated at Donetsk Regional Antitumor Center and University Clinic of Odessa in 2000–2014.
The results from complex treatment of regional breast cancer with unfavorable factors for prognosis of tumor growth due to developed methodology using the combination of introduction of selective intra-arterial and intravenous polychemotherapy in the basin of internal mammary artery in conjunction with radiological and hormonal therapy exceed the results from standard programs for treatment of patients with regional forms of breast cancer with performance of mammectomy and systemic chemotherapy.
The methodology, developed by authors, was recommended for wide application in such category of patients.