The search for new natural anti-inflammatory drugs is of current importance pharmacological problem. The plant raw material is an inexhaustible source of substances with different biological activity. The fruits of Capsicum annuum L. have anti-inflammatory activity, therefore the aim of our work was to study their phytochemical composition and medicinal properties in the conditions of experimental inflammation.
Using spectrophotometric methods of analysis, the quantitative constituent of capsaicinoids and carotenoids in different varieties of Capsicum annuum L. was determined. The study of anti-inflammatory properties of alcohol extracts Capsicum annuum L. fruits was carried out on the model of carrageenan-induced inflammation.
All the investigated varieties of pepper according to the content of capsaicinoids corresponded to the requirements of the Ukrainian state standard 14260-89, the requirements of the European Pharmacopoeia corresponded to the variety Astrakhanski and Ukrainian bitter. Using the treatment with alcohol extracts of pepper fruits carrageenan-induced inflammation, it was possible to achieve complete cure on the 7th day after the injection of phlogogen.