The critical coarctation of the aorta (CoA) is congenital heart defect, which makes up 10% of all congenital heart diseases and requirs surgery in the neonatal period. Severe heart failure develops in approximately 50% of infants with CoA and mortality ranges from 10% to 100% depending on its combination with complex congenital heart diseases.
Morphological investigation using general histological, histochemical, light microscopic techniquesrevealed a violation of elastogenesis, formation of focal or subtotal sclerotic and degenerative processes in the wall of the aorta, leading to disturbance of hemodynamics in the affected segment.